Leptin Levels and Weight Loss
What is Leptin?
Leptin is a hormone released from fat cells in adipose tissue. Leptin signals to the hypothalamus, an area of the brain which tells the body to eat. Leptin does not affect food intake from meal to meal but, instead, acts to alter food intake and control energy expenditure over the long term. Leptin has a more intense effect when we try to lose weight. This stimulates a larger appetite, cravings of carbs and sugars and increased food intake. The hormone helps us to maintain our normal weight and unfortunately for dieters, makes it hard to lose those extra pounds! High leptin levels will not recognize that your body has plenty of fat stored and you need to use this fat for energy. Your body just keeps storing more and more body fat.
How is Leptin Controlled?
Due tot the fact leptin is produced by fat cells, the amount of leptin released is completely related to the amount of body fat we store; so the more fat we have,, the more leptin we will have stored in our blood. As we increase our fat mass, leptin levels rise. Needless to say, leptin levels decrease if we decreases our body’s fat mass over a period of time also. Basically, we have to have a healthy ratio of body fat to lean mass to naturally control our lepton levels.
In other words, Leptin will tell the brain when to empty fat cells and utilize out fat for energy. To much Leptin and body fat can trigger the brain to feel as you need to eat more. Plus the brain does not see that there is enough “energy” or body fat that it can use. In hence, your body stores more and wants to eat more!
Semaglutide and Exenatide act as a communication barrier to allow the brain to release fat for energy.