GHK-CU – Copper Peptide Botox Altenative
How would you like to find an anti aging cream that can replace Botox, regenerate collagen, tighten skin and take years off your face? Well, you have just found it. GHK-CU Copper Peptide cream. This is only available through prescription. Results will be noticeable within a couple weeks.
GHK-Cu is a tripeptide naturally found in plasma, whose benefits have proven to be extraordinary, completely changing the way many foresee anti-aging techniques. This tripeptide has a copper component, which we may not realize is incredibly important for overall wellness.
GHK – Cu is a Copper facial foam Peptide and has clinical studies that indicate its variety of roles improving skin elasticity, regenerating collagen, reduces wrinkles and stimulate hair follicles for hair regrowth and thickness.
GHK is most fulfilled in young blood paths; although, it begins to decrease as we age and is reduced by about 60% by the age of 60. This coincides with the way that the skin regenerates and can greatly lead to the onset of visible aging. GHK-Cu has powerful anti-aging effects and can help regenerate aging skin by encouraging collagen growth and restoring elasticity.
These positive effects decline with age because the concentration of GHK-Cu in the body decreases with age. Thus, there is an increase in inflammation, cancerous activity, and tissue destruction. In plasma, the level of GHK-Cu is about 200 ng/ml at age 20. By the age of 60, the level drops to 80 ng/ml.
Benefits of GHK-Cu:
Tighten loose skin and reverse thinning of aged skin
Repair protective skin barrier proteins
Improve skin firmness, elasticity, and clarity
Reduce fine lines, depth of wrinkles, and improve structure of aged skin
Smooth rough skin
Reduce photodamage, mottled hyperpigmentation, skin spots and lesions
Improve overall skin appearance
Stimulate wound healing
Protect skin cells from UV radiation
Reduce inflammation and free radical damage
Increase hair growth and thickness, enlarge hair follicle size
GHK stimulates both synthesis and breakdown of collagen and glycosaminoglycans and modulates the activity of both metalloproteinases and their inhibitors. It stimulates collagen, dermatan sulfate, chondroitin sulfate, and the small proteoglycan, decorin. It also restores replicative vitality to fibroblasts after radiation therapy.
GHK-Cu FACIAL STUDIES:
Copper peptide GHK-Cu is widely used in anti-aging cosmetics (INCI name: Copper tripeptide-1). Several controlled facial studies confirmed the anti-aging, firming and anti-wrinkle activity of copper peptide GHK-Cu. Abdulghani et al. established that facial cream containing GHK-Cu increased collagen in photoaged skin of 20 female volunteers, performing better than vitamin C and retinoic acid. Leyden et al. conducted 12 weeks facial study of GHK-Cu containing face and eye cream, reporting significant improvement of skin laxity, clarity and appearance, reduced fine lines and the depths of wrinkles and increased skin density and thickness comparing to placebo. GHK-Cu eye cream performed better than vitamin K cream. Finkley et al. conducted 12-week facial study on 67 women and reported that GHK-Cu cream applied twice daily improved aged skin appearance, increased thickness, reduced wrinkles and strongly stimulated dermal keratinocyte proliferation as determined by histological analysis of biopsies. The same study found copper peptide GHK-Cu to be non-toxic and non-irritating.
HAIR GROWTH BENEFITS OF GHK-CU:
Copper peptide GHK-Cu and its analogs were found to strongly stimulate hair growth. The efficiency of synthetic analog of GHK-Cu was similar to that of 5% minoxidil.
Copper peptides are clearly occurring small protein fragments that have high affinity to copper ions. In human plasma, the extent of GHK-Cu is ready 200 µg/ml at age 20. By the age of 60, the level drops to eighty µg/ml. In human beings, tripeptide GHK-Cu can promote activation of wound recovery, appeal of immune cells, antioxidant and anti-inflammatory consequences, stimulation of collagen and glycosaminoglycan synthesis in pores and skin fibroblasts and merchandising of blood vessels increase. GHK is a safe, extensively studied compound that has a wealth of positive and health-promoting effects in many tissues and systems. It has been widely used in anti-aging and cosmetic products in humans for decades without any adverse effects and can be easily incorporated in creams, liposomes, foams or subcutaneous injections.
Abdulghani, AA, Sherr S, Shirin S, Solodkina G, Tapia EM, Gottlieb AB. Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin – A pilot clinical, histologic, and ultrastructural study. Disease Manag Clin Outcomes. 1998;1:136-141
Leyden J, Stephens T, Finkey MB, Appa, Y, Barkovic S, Skin Care Benefits of Copper Peptide Containing Facial Cream. Amer Academy Dermat Meeting, February 2002, Abstract P68, P69
Finkley MB, Appa Y, Bhandarkar S. Copper Peptide and Skin. Cosmeceuticals and Active Cosmetic, 2nd Edition, P. Eisner and H.I. Maibach (Eds.) Marcel Dekker, New York. 2005:549-563
Gorouhi, Farzam, and Howard I. Maibach. “Topical peptides and proteins for aging skin.” Textbook of Aging Skin. Springer Berlin Heidelberg, 2010. 1089-1117.
Pickart, Loren, Jessica Michelle Vasquez-Soltero, and Anna Margolina. “GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration.” BioMed research international 2015 (2015).
Pickart, Loren, Jessica Michelle Vasquez-Soltero, and Anna Margolina. “The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health.” Oxidative medicine and cellular longevity 2012 (2012)
Pickart L. The human tri-peptide GHK and tissue remodeling”. J. Biomater. Sci. Polymer Edn. 2008; 19(8):969-988 Peptide Sequence: Gly-His-Lys(Cu2+)