“G3” (Retatrutide) Triple Glucagon Peptide Agonist

The Next Generation GLP Weight Loss Injection – Now Available!

How Retatrutide Weight Loss Shots Work

“G3” Retatrutide is a triple agonist drug that works similarly to semaglutide and tirzepatide, but works in three different ways. Semaglutide targets your receptor of the GLP-1 hormone, which stabilizes your blood sugar, helping to reduce cravings while helping you to eat less, as well as slowing down your digestive system to help you feel fuller longer. Tirzepatide targets both the GLP-1 receptor as well as that of the GIP, which gives it a metabolic boosting factor that creates a better modality and efficiency for cell energy production. This makes it exceptional at helping with targeted fat loss. It also helps protect your muscles as well as limit nausea. Retatrutide, however, targets three different receptors—GLP-1, GIP, and glucagon—further helping you to feel less hungry and working to prevent overeating. Current Retatrutide phase 3 clinical trials have proven 92% participants have lost 24-30% of total body weight in as little as 48 weeks. This compared to Semaglutide 15-18%, and Trizepatide 20% total weight loss in 63 weeks. The “G3” compound is an excellent way to continue your weight loss from plateaus with other GLP medications. 

At MedShape weight Loss Clinic, we often start patients on semaglutide or tirzepatide if they are facing intolerable side effects or have hit a plateau with their weight loss. However, for those who have hit a plateau with either Semaglutide or tirzepatide,  or simply want to try the newest and most advanced weight loss shot option,”G3″  Retatrutide is now available. “G3” is a once weekly injection.

Scottsdale Weight Loss Clinic MedShape

Benefits of Retatrutide

Patients opting for Retatrutide through MedShape Weight Loss Clinics can experience numerous benefits that contribute to their weight loss journey and overall health improvement. This innovative medication offers a multi-faceted approach to weight management, addressing key factors that affect metabolism and appetite. By incorporating Retatrutide into their treatment plan, patients can expect the following benefits:

  • Reduced appetite, stronger than Tirzepatide and Semaglutide – Greater weight loss results and metabolic enhancement

  • Improved blood sugar control

  • Enhanced fat metabolism – Glucagon works on fat metabolism process

  • Increased energy levels – Better sustained energy levels

  • Reduced body fat percentage – More lean mass protection from Glucagon equals reduction in body fat loss

  • Better regulation of insulin levels

  • Support for healthy cholesterol levels

  • Hormone Optimization – Improves many hormone levels such as LH and Gherkin which controls metabolic functions as we age

  • Improves visceral fat and fatty liver

  • Much stronger than both Tirzepatide and Semaglutide

These benefits, combined with personalized treatment plans and ongoing support, ensure that patients achieve their weight loss goals and maintain long-term health improvements.

For maximum results, this compounded medication can be microdosed weekly alone or in conjunction with Tirzepatide or Semaglutide. Excellent way to accelerate weight loss when your current GLP seems to slow down after titration doses.

Information on “G3” Retatrutide

Retatrutide is a revolutionary weight loss peptide that operates through three distinct mechanisms to promote effective and sustainable weight management. It works by mimicking the action of natural hormones GLP-1, GIP, and glucagon, which play crucial roles in regulating appetite, insulin sensitivity, and energy expenditure. When patients come to MedShape Weight Loss Clinic, they can expect a comprehensive and personalized treatment plan. During the initial consultation, our team will assess their health and weight loss goals to determine the appropriate dosage and administration schedule. As patients begin their Retatrutide regimen, they will experience reduced appetite, improved blood sugar control, and enhanced fat metabolism, leading to gradual and sustained weight loss. Regular follow-up appointments ensure that the treatment is effective and adjusted as needed to achieve the best results.

Don’t love near a physical MedShape Weight Loss Clinic location? No problem! MedShape has licensed providers in 47 states. We can happily schedule a telemedicine consultation through phone or video modules to get your questions answered and get you started.

Though retatrutide is not yet FDA approved , the phase III clinical trial of this weight loss injection is currently underway, which means you can expect it to receive FDA approval sometime in 2026 or 2027. However, the treatment does not have to be FDA approved for us to know that the drug can be used safely. This science and peptide technology has been around for decades—it is the combination that is new, and it is the delivery system that is what makes it able to be patented by a drug manufacturer. 

“3G” Retatrutide is a triple agonist receptor peptide. (GIP, GLP-1 and glucagon) receptor agonists. All three of these medication components as individuals are FDA approved and have  been used for many years. All of MedShape’s medication are dispensed through reputable FDA approved 503a and 503b Compounding Pharmacies. Compound medications do not have to be FDA approved.